Scientific Publications

Brown Adipose Tissue Improves Whole Body Glucose Homeostasis and Insulin Sensitivity in Humans.
Diabetes; Chondronikola, M. et al; July 2014

Temperature-acclimated brown adipose tissue modulates insulin sensitivity in humans.
Diabetes; Lee, P. et al; June 2014

Activation and recruitment of brown adipose tissue as anti-obesity regimens in humans.
Ann Med; Yoneshiro, T. et al; June 2014

Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis.
Cell; Rao, RR. et al; June 2014

Brown adipose tissue and its therapeutic potential.
J Intern Med; Lidell, ME. et al; April 2014

Two types of brown adipose tissue in humans.
Adipocyte; Lidell, ME. et al; January 2014

Fat cells directly sense temperature to activate thermogenesis.
Proc Natl Acad Sci U S A; Ye L. et al; July 2013

Banting Lecture 2012: Regulation of Adipogenesis: toward new therapeutics for metabolic disease.
Diabetes
; Spiegelman B; June 2013

Evidence for two types of brown adipose tissue in humans.
Nature; Lidell M. et al; May 2013

Adaptive thermogenesis in adipocytes: is beige the new brown?
Genes & Development; Wu J. et al; February 2013

Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance.
Cell; Vernochet C. et al; December 2012

Turning on brown fat and muscle metabolism: hedging your bets.
Cell; Lee K. and Kahn C.; October 2012

FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis.
Genes & Development; Fisher F. et al; February 2012

TRPV4 is a regulator of adipose oxidative metabolism, inflammation and energy homeostasis.
Cell; Ye, L. et al; September 2012

Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human.
Cell; Wu, J. et al; July 2012

Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue.
Nature Medicine; Kiefer, F. et al; June 2012 

Targeted deletion of thioesterase superfamily member 1 promotes energy expenditure and protects against obesity and insulin resistance.
PNAS; Zhang, Y. et al; April 2012

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.
Nature; Boström, P. et al; January 2012

Different metabolic responses of human brown adipose tissue to activation by cold and insulin.
Cell Metabolism; Orava, J. et al; August 2011

Brown adipose tissue in humans.
International Journal of Obesity; Enerbäck, S.; October 2010

Human brown adipose tissue.
Cell Metabolism; Enerbäck, S.; April 2010

The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue.
The FASEB Journal; Zingaretti, M.C.; September 2009

The origins of brown adipose tissue.
New England Journal of Medicine; Enerbäck, S.; May 2009

Cold-Activated Brown Adipose Tissue in Healthy Men.
New England Journal of Medicine; Lichtenbelt, W., et al; April 2009

Functional brown adipose tissue in healthy adults.
New England Journal of Medicine; Virtanen, K.A. et al; April 2009

Identification and importance of brown adipose tissue in adult humans.
New England Journal of Medicine; Cypess, A.M. et al; April 2009

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.
Nature; Yu-Hua Tseng, Y.H et al; August 2008

PRDM16 controls a brown fat/skeletal muscle switch.
Nature; Seale, P., et al; August 2008

Unexpected evidence for active brown adipose tissue in adult humans.
American Journal Physiology Endocrinology and Metabolism; Nedergaard, J., Bengtsson, T., and Cannon, B.; August 2007